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Triphenylphosphine (TPP) | CAS: 603-35-0 | Key Ligand & Intermediate for Organic Synthesis

Triphenylphosphine (TPP) | CAS: 603-35-0 | Key Ligand & Intermediate for Organic Synthesis CAS NO.603-35-0

  • Min.Order: 10 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
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  • Product Details

Keywords

  • Triphenylphosphine
  • 603-35-0
  • TPP

Quick Details

  • ProName: Triphenylphosphine
  • CasNo: 603-35-0
  • Molecular Formula: C18H15P
  • Appearance: White crystalline powder
  • Application: Organic Synthesis; Homogeneous Catalys...
  • DeliveryTime: 30 days
  • PackAge: 25 kg/fiber drum, sealed with a double...
  • Port: qingdao port; shanghai port
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: ≥ 99.0% / ≥ 99.5% (Different grades av...
  • Storage: Store in a cool, dry, well-ventilated ...
  • LimitNum: 10 Kilogram

Superiority

Key Features & Benefits

  • High Versatility: A fundamental reagent in key synthetic transformations such as the Wittig, Mitsunobu, and Staudinger reactions.

  • Excellent Ligand: A vital phosphine ligand in homogeneous catalysis, used with metals like palladium, rhodium, and nickel for coupling reactions (e.g., Suzuki, Heck) and hydrogenations to stabilize the metal center and modulate its reactivity and selectivity.

  • Mild Reducing Agent: Capable of mildly reducing ozonides to aldehydes or ketones, and organic peroxides to alcohols.

  • High Purity Guaranteed: We offer high-purity grades (≥99.5%) to minimize side reactions, ensuring optimal yields and product quality.

  • Easy to Handle: A solid with a convenient melting point (80-82 °C), making it easy to weigh and add to reactions.

Details

Product Information

Item Content
Product Name Triphenylphosphine
Abbreviation TPP, PPh?
CAS No. 603-35-0
EINECS No. 210-036-0
Molecular Formula C??H??P
Molecular Weight 262.29 g/mol
Appearance White crystalline powder
Purity ≥ 99.0% / ≥ 99.5% (Different grades available)
Packaging 25kg Fiber Drum (with inner plastic bag) / Customizable

 

Product Description

Triphenylphosphine (TPP), CAS No. 603-35-0, is a cornerstone organophosphorus compound that plays multiple indispensable roles in modern chemical synthesis. It exists as a white crystalline solid that is relatively stable in air, making it easy to store and handle. Due to its unique electronic and steric properties, TPP is a preferred ligand for numerous metal catalysts and a core reagent in several classic named reactions in organic chemistry.

As a professional supplier of fine chemicals, we provide high-purity and consistently high-quality Triphenylphosphine. Whether your work involves the synthesis of pharmaceuticals, agrochemicals, and fragrances, or research and development in new materials and catalysis, our TPP provides a solid foundation for the success of your project.

 

Key Features & Benefits

  • High Versatility: A fundamental reagent in key synthetic transformations such as the Wittig, Mitsunobu, and Staudinger reactions.

  • Excellent Ligand: A vital phosphine ligand in homogeneous catalysis, used with metals like palladium, rhodium, and nickel for coupling reactions (e.g., Suzuki, Heck) and hydrogenations to stabilize the metal center and modulate its reactivity and selectivity.

  • Mild Reducing Agent: Capable of mildly reducing ozonides to aldehydes or ketones, and organic peroxides to alcohols.

  • High Purity Guaranteed: We offer high-purity grades (≥99.5%) to minimize side reactions, ensuring optimal yields and product quality.

  • Easy to Handle: A solid with a convenient melting point (80-82 °C), making it easy to weigh and add to reactions.

 

Main Applications

  1. Organic Synthesis:

    • Wittig Reaction: For the synthesis of alkenes, one of the most important methods for forming carbon-carbon double bonds.

    • Mitsunobu Reaction: For the stereochemical inversion of alcohols or their conversion to other functional groups.

    • Staudinger Reaction: For the reduction of azides to amines.

    • Appel Reaction: For converting alcohols to the corresponding alkyl halides.

  2. Homogeneous Catalysis:

    • A key component of Wilkinson's Catalyst [RhCl(PPh?)?] for the efficient hydrogenation of alkenes.

    • Used as a ligand in palladium-catalyzed coupling reactions for synthesizing complex organic molecules, drugs, and materials.

  3. Pharmaceutical & Agrochemical Industries:

    • A critical intermediate in the synthesis of numerous Active Pharmaceutical Ingredients (APIs), including antibiotics, vitamins, and steroids.

    • Used in the production of various high-efficiency, low-toxicity pesticides, such as herbicides and insecticides.

  4. Other Applications:

    • Starting material for the synthesis of quaternary phosphonium salt phase-transfer catalysts.

    • Used in the synthesis of phosphorus-containing flame retardants.

 

Technical Specifications

Analysis Item Specification - Premium Grade
Appearance White crystalline powder
Assay, % by GC ≥ 99.5
Melting Point, °C 79.0 - 82.0
Moisture, % ≤ 0.1
Triphenylphosphine Oxide (TPPO), % ≤ 0.3
Note: Different grades are available. Please contact us for the COA of a specific batch.  

 

Packaging & Storage

  • Packaging: 25 kg/fiber drum, sealed with a double-layer polyethylene inner bag.

  • Storage: Store in a cool, dry, well-ventilated warehouse. Keep away from fire, heat sources, and strong oxidizing agents. Keep container tightly sealed to prevent moisture absorption and oxidation.

 

Why Choose Us?

  • Reliable Quality: Strict quality control ensures low impurity levels, especially the effective control of the critical impurity, Triphenylphosphine Oxide (TPPO).

  • Stable Supply: A strong and integrated supply chain guarantees long-term, stable availability.

  • Technical Support: Our team can provide you with technical consultation for your synthesis applications.

  • Competitive Pricing: We optimize our costs to offer you highly competitive market prices.

Contact us today for the latest quotation and samples of Triphenylphosphine!

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